I'd like to point out that the game, while most of the Agaran Menace related things are inaccessible, still includes some attainable objects that vaguely point towards the Agarans in a negative way, these objects being the Mushhroom Biome objects. The ones I'm talking about in particular are the lamp and the chest. Glitch descriptions say that: (Lamp) "Analysis. The glow is produced by spores which seem to display parasitic behaviour." (Chest) "Analysis. Opening this chest releases invisible spores. Long term effects are unknown." Other than that, nothing else really points to them negatively as of now (that I know of).