I don't think we really need another <mammal>-person race. We've already got one and a few bordering on being one. I do like the idea of a mutation that cannot be reversed and has bonuses, but also negatives. Maybe certain races such as humans and florans attack on sight, due to the formers mythology around them and being afraid, and the laters hunting style of life making them think it would be a fantastic hunt to hunt a strong, fast, bipedal wolf. Perhaps silver weapons and a new silver bullet ammo type could have their damage multiplied as well.