Need Help! Game Crashes Computer!

I posted a similar thread earlier, but I thought I'd post a more detailed one now since it didn't turn up much. After 5-15 minutes of gameplay, the screen will turn grey, and a few second later the music will cut out and be replaced with a dull buzzing. At this point I can't do anything (task manager/exit the program) and I'm forced to restart my computer. I can't finish a single game unless I save and quit after the first level. Any help would be GREATLY appreciated! Specs are below, since someone told me I should post them. If I've missed anything important, let me know.

Windows 7 64-bit Operating System
Processor: Intel(R) Core(TM) i5-2500 CPU @ 3.30GHz 3.30GHz
Installed Memory (RAM): 8.00 GB
Graphics card: AMD Radeon HD 6900 Series

P.S: I'm pretty sure it isn't overheating; the tower is clean inside and the fans are all working, and the basement is cold.

 

I have heard issues with certain GPUs before in relation to Game Maker, which is what this game was made in. I can't tell for sure if this would be the case with the card you use, but it might be worth looking into.

 

I have similar problem. Though sometimes I can play as long as I die, but this is quite rarely have gotten to play about 4 longer games (over 60 minutes). Anyway it seems to me that the problem is that the graphics card crashes and thus crashes the whole computer and restart is the only available option.

I have had this problem at first version and also both 1.0.0 and 1.0.1

OS: Windows 7 64-bit 8GB memory
Processor: Intel(R) Core(TM) i7-2600K CPU @ 3.40GHz
Graphics card: ASUS EAH6970 Series

 

I'm noticing not just AMD, but specifically the HD 6900 series? i got a 6950 myself and this crash hits me at seemingly completely random, very frustrating as it decided to crash like this right when i was snowballing hard on my first Huntress playthrough last night:

Operating System: Windows 7 Ultimate 64-bit (6.1, Build 7601) Service Pack 1
Processor: AMD Phenom(tm) II X4 965 Processor (4 CPUs), ~3.4GHz
Card name: AMD Radeon HD 6900 Series
Manufacturer: Advanced Micro Devices, Inc.
Driver File Version: 8.17.0010.1124 (English)
Driver Version: 9.12.0.0

i've heard that AMD drivers tend not to work so well, and i got this crash more often before i updated to Catalyst 13.1 a few weeks ago (control panel can't open for some reason), but this is the only game crashing my video card atm, so i'm not going to play RoR in the marathon sessions i was previously as i'll just start getting pissed at it

 

I have a 6990 gpu and my game crashes almost instantly.
I can't remember the last time any game crashed on this computer. Usually stuff just works.
My computer is like a litmus test for a buggy game vs. a user error.

 

Bump,
would appreciate a developer response...
Thanks.

 

I've had similar on a HD 5870.

Game would glitch out in different ways, screen would get some flickering effects (like.. 20 pixels missing for one frame) after closing game and a few other things.

This seems to go away when running the game as admin.

 

Thanks. Running as admin stopped the crashes.